Was a tincture or tea of white willow used as a folk medicine for generations until it got studied and the compound in it isolated by Bayer
Cocaine.
Indigenous population would chew coca leaves as a stimulant for various reasons and someone figured found out about it, studied it, and found out how to isolate the active compound and now we have Cocaine
Opiates
Opium Poppy was used for centuries for a variety of uses, but mostly recreational in the form of opium, then it got studied and turned into some of the most effective painkillers we have. (Morphine, codeine, heroin are naturally derived opium compounds, some others are synthetic or a blend such as oxycodone, methadone, fentanyl, carfentanyl)
Edit: white birch bark(I’m not 100% certain this is the right tree, but it was a tree, please correct me if I’m wrong) found the correction in another comment
Aspirin.
Was a tincture or tea of white willow used as a folk medicine for generations until it got studied and the compound in it isolated by Bayer
Cocaine.
Indigenous population would chew coca leaves as a stimulant for various reasons and someone figured found out about it, studied it, and found out how to isolate the active compound and now we have Cocaine
Opiates
Opium Poppy was used for centuries for a variety of uses, but mostly recreational in the form of opium, then it got studied and turned into some of the most effective painkillers we have. (Morphine, codeine, heroin are naturally derived opium compounds, some others are synthetic or a blend such as oxycodone, methadone, fentanyl, carfentanyl)
Edit:
white birch bark(I’m not 100% certain this is the right tree, but it was a tree, please correct me if I’m wrong)found the correction in another comment