Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
Lots of people seem to think that losing weight is simply a matter of calories in and calories out, and if calories in exceeds your BMR then stop eating. But that’s like saying that gambling is a matter of winnings and losses, and if the losses exceed your budget then stop gambling. Simple enough for the average person, but obviously useless advice for someone who has a problem.