Pic taken from roadway.report, an interactive map of all known roadway deaths in the USA.
Fatalities resulting from motor vehicle crashes are the third largest cause of accidental deaths in the United States. On average for 2024 there were over 100 deaths per day on US roads.
Rural areas also have less well-maintained roads, poorer lighting, and more wildlife that may run into the road, in addition to requiring more driving because everything is further apart.