The Canadian entrepreneur has always pushed the boundaries of gene editing, once attempting to turn horses into unicorns. Now she is set on modifying human embryos – something her controversial ex-husband was jailed for doing
Many genetic disorders persist in the human population because they can confer a genetic advantage.
Sickle cell anemia carriers are resistant to malaria.
Tay Sachs carriers are resistant to tuberculosis.
Huntington disease carriers have less cancer risk.
This is illegal to do in most countries because we don’t want to fuck around and find out with the human genome, which is full of remnants of ancient viruses.
As a starter, I’m extremely sceptical of modifying the genome of embryos (as I hope was clear from my comment). Like you said, there’s plenty of defects that can have advantageous sides in addition to the negative sides. My point is that the only way this could even conceivably be ethical to do, is if it was used to remove diseases.
I believe there’s already a procedure they do to remove a disease carried in the mother’s mitochondria. I heard about a rare disease from my dentist the other day that causes people to never grow any teeth. I’m saying that if this is done, then the only ethical thing to do is use it for population-wide removal of severe diseases with no known positive sides, and even that can be dubious (as you point out).
Many genetic disorders persist in the human population because they can confer a genetic advantage.
Sickle cell anemia carriers are resistant to malaria.
Tay Sachs carriers are resistant to tuberculosis.
Huntington disease carriers have less cancer risk.
This is illegal to do in most countries because we don’t want to fuck around and find out with the human genome, which is full of remnants of ancient viruses.
As a starter, I’m extremely sceptical of modifying the genome of embryos (as I hope was clear from my comment). Like you said, there’s plenty of defects that can have advantageous sides in addition to the negative sides. My point is that the only way this could even conceivably be ethical to do, is if it was used to remove diseases.
I believe there’s already a procedure they do to remove a disease carried in the mother’s mitochondria. I heard about a rare disease from my dentist the other day that causes people to never grow any teeth. I’m saying that if this is done, then the only ethical thing to do is use it for population-wide removal of severe diseases with no known positive sides, and even that can be dubious (as you point out).
The precision of gene editing has been vastly oversold.