Seinfeld- Jerry and Elaine are exes and breify get back together at the end of season one
Friends- lots of romantic entaglements but mainly Chandler/Monica, Ross/Rachel, and Joey/Rachel
How I Met Your Mother - two of the main characters are a steady couple, the other three are a love triangle
Big Bang Theory- by the end, it’s three couples and one single guy
Any shows like these where the main characters never date each other or hook up with each other?
That’s only if you only consider the 3 main characters. They each have relationships with recurring characters.
The discussion is whether there is a show where the main group of friends have no romantic entanglements WITHIN THE GROUP. So yes, Only Murders in the Building qualifies unless the main three date or hook up with eachother