I did tirzepatide. Like others have said, the food noise went away and I lost about 2.5lbs a week. Mild constipation and having a drink didn’t give me the same “hit” of pleasure. Make sure he gets enough protein and works out to prevent losing too much muscle. It definitely felt like a miracle drug but being off of it for a month, I can see why people stay on long term. The food cravings came back and I’m having to be real careful not to eat too much and gain it all back.

I had the opposite effect. 2 or 3 days between poops.

Toastmasters is the best piece of advice in this thread.

That’s interesting. I don’t have any kind of engineering background and not sure what to Google. Are there examples of this?

That has nothing to do with the shape of the casing, which never travels through the barrel. The bullet itself is still round in this picture.

Highly dependent on the people involved. My oldest friend I’ve known since high school. We’ll occasionally send a meme back and forth but he’d never even met my kids until they were in their teens. We live far apart. But when my dad passed and I needed his help with something, he dropped everything and drove 6 hours round trip to be there. I probably see him or have a substantive conversation with him once or twice a year.

Design failure or design intent?

Aside from the outcome, it’s crazy that in 2001 there were still enough “Internet non-users” to make gathering data on them statistically significant

The goal is to make sure doctors, not advertising budgets, determine which medicines are prescribed, prevent medical overconsumption, and help keep health costs in check.

What a wild concept

The story is somehow even weirder than the headline.