Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
What I think some people ignore is that “food drive” is a thing. When I get hungry, and I know there’s food around, there’s no stopping me from eating. It’s most strong following days of intense exercise for me, but I know other have it worse than me.
There’s other reasons to, just like how we need to ask why someone is doing drugs, we also need to ask why they are eating food. GLP-1 are amazing because they can give you a head start on weight loss. But if you never do the work to understand what’s making you gain weight in the first place they’re basically useless.
A friend of mine got a gastric bypass and lost a ton of weight. She was super happy with her body and life improved a lot. Then life got very stressful and she became an alcoholic again. No we she’s gained weight again. The article is about a better weight loss formulation that doesn’t use GLP, but instead using glucagon and GIP peptides. I guess it’s got less side effects, maybe.
Same, the only way I found to not eat crisps every day is to not have any at home, otherwise I would eat half a bag a day. I buy 1-2 bags a month, go through them in less than a week, by which point I’m disgusted enough to easily hold out until next month. Bc never eating crisps sounds sad, but if I know I can eat them again in ~3 weeks, I don’t feel tempted when I see them in the shop meanwhile 🤷
The food noise is miserable. It’s cruel and mean! Hate it.
Isn’t part of the reason why GLP-1 drugs work so well, is because they do something that interferes with that “food drive”? I think it’s different than gastric bypass in that way
I think is the other way around. They extend the “I’m fullfil” hormone like from minutes to hours, so people don’t find themselves snacking an hour after eating
Yes, but the problem is that these are not meant to be forever drugs. You’re supposed to take them in conjunction with changing diet and exercise habits so that you can go off the drug and maintain a healthy weight on your own. Often people get off of these drugs without having done the work, and they end up right back where they started.