“inflammation is now understood to be a key mediator of OA that contributes to cartilage loss and progressive degeneration of affected joints… OA is no longer considered a noninflammatory arthritis or a ‘wear and tear’ disease”
I heretofore thought age-related cartilage loss was the cause of osteoarthritis and inflammation. Turns out it’s the other way around: the inflammation degrades cartilage. Okay, no more slogging through joint pains for me, regardless of how small.
Edit: added a phrase for clarity



RA… oof. That shit is a curse*, a giant FU from the universe. I hope you get the relief/management you need. Tangential: does the prednisone get you all hyper?
*My aunt had it. In my pre-teens, my mother sent me to live with and care for her in final years (it wasn’t the RA that got her), so I deeply empathize with your health struggles.
I imagine this to be no easy task for anyone, especially a pre-teen.