“inflammation is now understood to be a key mediator of OA that contributes to cartilage loss and progressive degeneration of affected joints… OA is no longer considered a noninflammatory arthritis or a ‘wear and tear’ disease”

I heretofore thought age-related cartilage loss was the cause of osteoarthritis and inflammation. Turns out it’s the other way around: the inflammation degrades cartilage. Okay, no more slogging through joint pains for me, regardless of how small.

Edit: added a phrase for clarity

  • xep@discuss.online
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    26 minutes ago

    When I started on a low inflammation elimination diet it did wonders for my joint pain. Can recommend.

    • roofuskit@lemmy.world
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      1 hour ago

      Low impact exercise is a great tool for reducing inflammation. Vitamin D is also an important part of regulating your immune system. Anything that supports a healthy immune system will help regulate its response and reduce inflammation.

  • Reyali@lemmy.world
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    3 hours ago

    Here I am staring at my sausage-like thumb that’s been swollen like this for three days thanks to rheumatoid arthritis. This article gives good context for why RA often results in OA at a younger age. Maybe I will go take a prednisone and apply another dose of diclofenac to try to knock this inflammation down…

    • roofuskit@lemmy.world
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      1 hour ago

      There have been some good medications for RA created in the last decade or so. Has your rheumatologist prescribed anything longer term than prednisone? Prednisone is not really a long term safe solution.

    • JayleneSlide@lemmy.worldOP
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      3 hours ago

      RA… oof. That shit is a curse*, a giant FU from the universe. I hope you get the relief/management you need. Tangential: does the prednisone get you all hyper?

      *My aunt had it. In my pre-teens, my mother sent me to live with and care for her in final years (it wasn’t the RA that got her), so I deeply empathize with your health struggles.

      • kamenlady@lemmy.world
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        2 hours ago

        In my pre-teens, my mother sent me to live with and care for her in final years

        I imagine this to be no easy task for anyone, especially a pre-teen.

  • digitalFatteh@lemmy.ca
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    3 hours ago

    My back and knees tingle reading this. Just waiting on the knee cortisone inflammation to ease off 😉

    • JayleneSlide@lemmy.worldOP
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      3 hours ago

      Bruddah/sistah/non-binaryah, I know your pain intimately. I got my first shot in the knee 3 months ago. “And to think… I hesitated.” Sending warm recovery thoughts your way. What kind of physical therapy regimen does the sawbones have you on?

      • Onomatopoeia@lemmy.cafe
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        3 hours ago

        Read up on cortisone - related cartilage/tendon concerns.

        Your doc probably overstates the risk a great deal. Check NLM for studies, it looks like there’s a risk, but all the studies are of patients with injury and on-going degeneration. By the time you get to injections you’ve exhausted other treatments.

  • leoj@piefed.social
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    2 hours ago

    Link above just forces me to do captchas over and over again… am I really that bad at finding the stairs, or is this a bug?