Hear me out, measles can cause immune system amnesia. People with autoimmune disorders have immune systems that want to kill them. What if we use the immune system amnesia property of measles to reset the immune system of people suffering with autoimmune disorders? Maybe we could do some crispr on the measles virus to make it not as dangerous or something like that first though.
Aside from some comments mentioning how immune reset therapies are in fact a thing through either antibody or chemical depletion of your immune cells. These can show improvement but it is very far from curative and not too much better chances than existing immune suppression stuff.
The danger to an immune “reset” are that you are generally then able to be reinfected with every cold and flu as well. This is dangerous for older or already fragile people. The existing therapies reduce this danger by not entirely wiping memory cells out but that also means they aren’t always curative.
Beyond that autoimmune diseases in general are a mix of genetics and environmental factors (and even gut bacteria by some studies). If the underlying problem isn’t fixed then relapse is a question of when not if. It’s like adding fluid to a container with a leak, eventually you’re going to have to add more again unless you fix the leak first.
So we have to find where the “leaks” are, what they are caused by and fix the cause(s) to have something that is an actual cure. Right now we mostly know where the leaks are and some causes and can patch some up leaks up. However, we don’t have a way to fix the causes yet and we dont know all of them.
*I am a cell bio PhD but not an immunology specialist.