“inflammation is now understood to be a key mediator of OA that contributes to cartilage loss and progressive degeneration of affected joints… OA is no longer considered a noninflammatory arthritis or a ‘wear and tear’ disease”

I heretofore thought age-related cartilage loss was the cause of osteoarthritis and inflammation. Turns out it’s the other way around: the inflammation degrades cartilage. Okay, no more slogging through joint pains for me, regardless of how small.

Edit: added a phrase for clarity

  • Reyali@lemmy.world
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    3 hours ago

    Here I am staring at my sausage-like thumb that’s been swollen like this for three days thanks to rheumatoid arthritis. This article gives good context for why RA often results in OA at a younger age. Maybe I will go take a prednisone and apply another dose of diclofenac to try to knock this inflammation down…

    • roofuskit@lemmy.world
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      1 hour ago

      There have been some good medications for RA created in the last decade or so. Has your rheumatologist prescribed anything longer term than prednisone? Prednisone is not really a long term safe solution.

    • JayleneSlide@lemmy.worldOP
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      3 hours ago

      RA… oof. That shit is a curse*, a giant FU from the universe. I hope you get the relief/management you need. Tangential: does the prednisone get you all hyper?

      *My aunt had it. In my pre-teens, my mother sent me to live with and care for her in final years (it wasn’t the RA that got her), so I deeply empathize with your health struggles.

      • kamenlady@lemmy.world
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        2 hours ago

        In my pre-teens, my mother sent me to live with and care for her in final years

        I imagine this to be no easy task for anyone, especially a pre-teen.