Certain medicines take regimines to reach full effect, either because they need to build up in your system, or because they allow your body to recover while you are on them, which eventually causes a net gain. I believe stimulants are usually the latter.
When I’m unmedicated, fatigue builds up faster, which makes me more miserable overall, and that compounds. One dose of my med isn’t enough to wipe away all the exhaustion from being unmedicated for weeks. I have to be on it for a while before I get the full effect, which is essentially just being in a good mood most of the time ime.
I was recently sick myself, and did the same where I stopped taking my med. I now think that’s actually a mistake. I spoke with my wife about it, who has been on ADHD meds a lot longer than I have, and that’s what she told me as well. Your meds help your body function. Not taking them while you’re sick is counterproductive



Unfortunately, the only way I’ve found to avoid this is to be on top of my responsibilities