I mean like, what is it about standing or even light movement that is so distinct on a biological/cellula level?
The appeal to whats natural or kind of teleollogical doesnt address that, like is there an actual material theory about “this is your body on sitting…”
Purely a guess on my part, but I imagine a not-insignificant amount of this is simply bloodflow. If cancer is a disruption in the cellular replication mechanics, then we’re looking at protein folding, DNA replication, and ion pumps and cell stuff. Perhaps not “taking out the trash” via blood flow allows higher rates of cellular corruption? Maybe lower bloodflow results in weaker cell self-destructs? Lots of candidates…
It sure does! Blood is carried back to the spleen, kidney, and liver where the blood is “cleaned” of the waste it was carrying before being recirculated. It also carries immune cells to/from your lymph nodes, oxygen, water, all sorts of stuff. Blood is more than just WBC/RBC!
Since we’re guessing, I’d guess lymph is part of it. It’s part of our immune systems, but, unlike blood which has its own pumping mechanism (the heart), lymph gets moved along passively.
There’s one paradoxical-seeming fact that adult humans generally use the same amount of calories each day regardless of their physical activity level. There are exceptions, but they are extreme cases, like professional athletes pushing their limits.
It makes sense if you think about it. Processes that give us access to energy aren’t exactly fast, so our bodies will just be producing that energy regardless so it’s there if we need it. But when we don’t, any cells can grab them up to do their cell things, which includes cancer cells (which we all have but are mostly benign), giving them more chances to make more mistakes copying DNA, which rolls the dice more often on picking up some of those mutations that make them dangerous or deadly.
It’s also why you lose weight in the kitchen rather than the gym. Your body isn’t doing anything differently with the food you eat whether you take a nap or go for a run.
I mean like, what is it about standing or even light movement that is so distinct on a biological/cellula level?
The appeal to whats natural or kind of teleollogical doesnt address that, like is there an actual material theory about “this is your body on sitting…”
Good question, apparently there’s stuff we understand and stuff we don’t.
Im curious if reclining is as bad, I very rarely (almost never actually “sit”, more of a divan guy
Purely a guess on my part, but I imagine a not-insignificant amount of this is simply bloodflow. If cancer is a disruption in the cellular replication mechanics, then we’re looking at protein folding, DNA replication, and ion pumps and cell stuff. Perhaps not “taking out the trash” via blood flow allows higher rates of cellular corruption? Maybe lower bloodflow results in weaker cell self-destructs? Lots of candidates…
Does blood “take out the trash too”, i didnt realize it serves that dual function. Like I knew it transports oxygen and maybe nutrients vaguely…
It sure does! Blood is carried back to the spleen, kidney, and liver where the blood is “cleaned” of the waste it was carrying before being recirculated. It also carries immune cells to/from your lymph nodes, oxygen, water, all sorts of stuff. Blood is more than just WBC/RBC!
Blood is the lifeblood of the body!
Not joking, has anyone studied the potential anti-cancer benefits of substances that stimulate blood flow like caffeine and niacin?
I’m not sure, but that could be interesting.
Since we’re guessing, I’d guess lymph is part of it. It’s part of our immune systems, but, unlike blood which has its own pumping mechanism (the heart), lymph gets moved along passively.
There’s one paradoxical-seeming fact that adult humans generally use the same amount of calories each day regardless of their physical activity level. There are exceptions, but they are extreme cases, like professional athletes pushing their limits.
It makes sense if you think about it. Processes that give us access to energy aren’t exactly fast, so our bodies will just be producing that energy regardless so it’s there if we need it. But when we don’t, any cells can grab them up to do their cell things, which includes cancer cells (which we all have but are mostly benign), giving them more chances to make more mistakes copying DNA, which rolls the dice more often on picking up some of those mutations that make them dangerous or deadly.
It’s also why you lose weight in the kitchen rather than the gym. Your body isn’t doing anything differently with the food you eat whether you take a nap or go for a run.