• brognak@lemmy.dbzer0.com
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    1 day ago

    Eh, I would argue weed doesn’t destroy people’s lives. Not to say it’s helping but it’s never the root cause. If they stopped smoking weed, their lives would probably get better, but again probably a lot of underlying issues that also need to be addressed.

    Alcohol 100% the root cause of peoples fucked up lives. If they stopped drinking, most of their problems would disappear overnight (until the DTs hit…), and their lives would get better from that point.

    Maybe I am an asshole, but that’s how I see it and watching three wasted fucked heads get hauled off in cuffs (one because they swung on staff) from a concert this week isn’t helping while I was standing their stoned out of my gourd laughing my ass off at them getting manhandled because of their own idiotic decisions. Then I went back to vibing out to metal, and ate a burger after.

    Alcohol is literally the second worst substance we mass produce only behind petrochemicals.

    • Maeve@kbin.earth
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      1 day ago

      I didn’t realize how much weed warped my thinking, until I’d been clean a few months.

    • BCsven@lemmy.ca
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      1 day ago

      I saw it first hand. Friend lost his wife and house to weed. Two other people in our circles had weed psychosis. Thankfully early intervention helped them recover. But we also know one person that went into it never recovered. And became a danger to those around him. Now he’s in jail.

      It happens with alcohol too, but not the everlasting schizo issues

      • Maeve@kbin.earth
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        1 day ago

        Eh, I’d bet alcohol is more on the everlasting schizophrenia risk side. But weed really does fuck up your thinking.

        Like every occasional sixth month or year in a conducive environment, yes, it may enhance thinking outside the box for an insight or few. Daily would be like a milder version of dropping hallucinogens.

        • BCsven@lemmy.ca
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          1 day ago

          Studies have shown a direct link to weed induced schizo disorders and those with genetic markers susceptible for it. Getting a DNA test is not on most peoples priority list.

            • BCsven@lemmy.ca
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              24 hours ago

              I think the science paper I read was 7x higher rate on weed, ifyour had a certain gene. I will have to find it

              • Maeve@kbin.earth
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                24 hours ago

                That’s still not statistically significant, and correlation does not imply causation. It serves as a caution, and I’m inclined to agree it’s not wise to risk it, but let’s be honest with ourselves and others.

                • BCsven@lemmy.ca
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                  21 hours ago

                  Well correlation studiear say 37% risk, but I recognize that correlation is not causation, however they have found the mechanism that causes the increased psychosis with genes.

                  https://www.mdpi.com/2076-3417/12/20/10464

                  AKT1 gene polymorphism rs2494732 as the main genetic factor

                  C allele homozygosity significantly increases psychosis risk in cannabis users.

                  Mechanism: Cannabis consumption slows AKT1 functionality, releasing greater dopamine in the striatum through indirect mechanisms.

                  COMT and DAT1 gene interactions compound the risk

                  CB-1 receptor activation leading to increased dopamine release and GABA inhibition